Accredited at “A++” grade (highest level as per modified criteria notified on 27.07.2017) by NAAC and Conferred “University with Potential for Excellence” status by UGC


Department :  Moleculary Biology & Biochemistry

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Name:Dr. Gagandeep Kaur Gahlay
Areas of Interest / SpecializationReproductive Biology
e Mail:gaganbejoy@gmail.com
Best Ten Publications:1. Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K (2013). The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation. J Biol Chem. 288(27): 19900-14. 2. Gao Y, Aryal RP, Ju T, Cummings RD, Gahlay G, Jarvis DL, Matta KL, Vlahakis JZ, Szarek WA, Brockhausen I (2013). Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans. Biochim Biophys Acta. 1830(8): 4274-81. 3. Gahlay G, Gauthier L, Baibakov B, Epifano O and Dean J (2010). Gamete Recognition in mice depends on the cleavage status of an egg's zona pellucida protein. Science. 329:216-219. 4. Gahlay GK, Batra D, Gupta SK (2005). Baculovirus expressed C-terminal fragment of bonnet monkey (Macaca radiata) zona pellucida glycoprotein-3 inhibits ZP3-mediated induction of acrosomal exocytosis. Mol Reprod Dev. 71:237-244. 5. Sivapurapu N, Hasegawa A, Gahlay GK, Koyama K and Gupta SK (2005). Efficacy of antibodies against a chimeric synthetic peptide encompassing epitopes of bonnet monkey (Macaca radiata) zona pellucida-1 and zona pellucida-3 glycoproteins to inhibit in vitro human sperm-egg binding. Mol Reprod Dev. 70: 247-254. 6. Gahlay GK and Gupta SK. (2003) Glycosylation of zona pellucida glycoprotein-3 is required for Inducing acrosomal exocytosis in the bonnet monkey. Cell. Mol. Biol. (Noisy-le-grand). 49:389-397. 7. Gahlay GK, Srivastava N, Govind CK and Gupta SK. (2002) Primate recombinant zona pellucida proteins expressed in Escherichia coli bind to spermatozoa. J Reprod Immunol. 53: 67-77. 8. Govind CK, Gahlay GK*, Choudhury S and Gupta SK. (2001) Purified and refolded recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B expressed in Escherichia coli binds to spermatozoa. Biol. Reprod. 7: 532-538. 9. Patra AK, Gahlay GK*, Reddy BVV, Gupta SK and Panda AK. (2000) Refolding, structural transition and spermatozoa-binding of recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-C expressed in Escherichia coli. Eur. J. Biochem. 267: 1-8.
Awards and Honours:DBT-CTEP Travel Award 2016 Travel Award, 2012 Glycobiology Conference, USA Gerald D Aurbach Memorial Scholarship, 2008, FAES, National Institutes of Health, USA Gerald D Aurbach Memorial Scholarship, 2007, FAES, National Institutes of Health, USA Fellows Award for Research Excellence (FARE) Award, 2007, National Institutes of Health, USA Nancy Nossal Fellowship Award, 2006, NIDDK, National Institutes of Health, USA